Prenatal ultrasound diagnosis of fetal microphthalmia
10.3760/cma.j.issn.1004-4477.2019.10.010
- VernacularTitle: 胎儿小眼畸形的产前超声诊断经验
- Author:
Lihong WU
1
;
Hongning XIE
;
Lijuan LI
;
Liu DU
;
Ju ZHENG
Author Information
1. Department of Ultrasonic Medicine, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
- Publication Type:Clinical Trail
- Keywords:
Ultrasonography;
Prenatal diagnosis;
Microphthalmia;
Associated malformations
- From:
Chinese Journal of Ultrasonography
2019;28(10):878-881
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the ultrasonic features, associated malformations and combined genetic abnormalities of microphthalmia .
Methods:The characteristics of 15 cases of fetal microphthalmia were retrospectively analyzed. And the proportion of fetal microphthalmia associated malformations were further assessed according to the different organ system.
Results:All the orbital diameters of affected eyes of the 15 cases were less than the 5th centile of normal fetal orbital diameter corresponding to gestational age. In which, 26.67%(4/15) fetuses had additional ocular defects, and 66.67%(10/15) were diagnosis with extrocular defects, including 20.00%(3/15) with central nervous system defects, 13.33%(2/15) with orofacial defects, 26.67% (4/15) with cardiac defect, 13.33%(2/15) with limb defect, 33.33% (2/15) with urogenital defect and 40.00%(6/15) with abnormal ultrasonographic soft markers. And the proportion of fetal microphthalmia associated extrocular defects showed no significant difference(P=0.502).
Conclusions:Fetal microphthalmia is frequently associated with random and sporadic occurrence of extrocular defects
