Albumin-to-bilirubin scores for assessing the prognosis in autoimmune hepatitis-related cirrhosis
10.3760/cma.j.issn.1007-3418.2019.10.007
- VernacularTitle: 白蛋白-胆红素评分在自身免疫性肝炎肝硬化预后评估中的应用
- Author:
Yan SONG
1
;
Hu YANG
2
;
Lin LIN
3
;
Kui JIANG
1
;
Wentian LIU
1
;
Bangmao WANG
1
;
Rui LIN
1
Author Information
1. Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China
2. Department of Nephrology, Tianjin Medical University NO.2 Hospital, Tianjin 300211, China
3. Department of Internal Medicine, Tianjin Medical University General Hospital Airport Hospital, Tianjin 300308
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Hepatitis, autoimmune;
Albumin-billirubin score
- From:
Chinese Journal of Hepatology
2019;27(10):772-776
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the prognostic value of albumin-to-bilirubin scores in the assessment of autoimmune hepatitis-related cirrhosis.
Methods:The receiver operating characteristic curve was used to evaluate the accuracy of ALBI, Child-Pugh and model for end-stage liver disease (MELD) for prognosis prediction. Survival analysis was performed according to the ALBI classification. Spearman correlation analysis was performed on the ALBI score and the Child-Pugh score. Survival curves were plotted by Kaplan-Meier method, and Log-rank method was used to compare the survival difference curves between different groups.
Results:149 patients were recruited in the study. The ROC analysis showed that the ALBI scores (0.861, 0.826, 0.779, 0.744)was superior to Child-Pugh scores(0.703, P = 0.006; 0.672, P < 0.001; 0.613, P < 0.001; 0.583, P < 0.001)and MELD score(0.774, P = 0.031; 0.731, P = 0.007; 0.669, P < 0.001; 0.631, P < 0.001) for predicting 6, 12, 24, and 36 months mortality. Patients with ALBI grade 3 had a significantly lower survival rate than those with ALBI grade1 and grade 2.
Conclusion:ALBI score may be useful to evaluate the long-term prognosis of patients with autoimmune hepatitis-related cirrhosis.
