A Rare Case of Pulmonary Epithelial-myoepithelial Carcinoma: Case Report and Literature Review.
10.3779/j.issn.1009-3419.2020.02.08
- Author:
Liang CHEN
1
;
Qingshu LI
2
;
Guang FU
1
;
Mingjian GE
1
Author Information
1. Department of Thoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
2. Department of Pathology, Chongqing Medical University, Chongqing 400016, China.
- Publication Type:Journal Article
- Keywords:
Diagnosis;
Immunohistochemistry;
Lung epithelial-myoepithelial carcinoma;
Treatment
- From:
Chinese Journal of Lung Cancer
2020;23(2):127-132
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Pulmonary epithelial-myoepithelial carcinoma is a very rare type of salivary gland lung tumor. No standard treatment plan yet. This article intends to analyze the clinical characteristics of pulmonary epithelial-myoepithelial carcinoma and discuss the diagnosis and treatment of pulmonary epithelial-myoepithelial carcinoma.
METHODS:The clinical data of a patient with pulmonary epithelial-myoepithelial carcinoma were analyzed and other relevant clinical literatures were reviewed.
RESULTS:Epithelial cells immunohistochemically expressed cytokeratin and myoepithelial cells immunohistochemically expressed SMA and S-100. The next-generation sequencing was mainly HRAS gene mutation and the express of PD-L1 protein was negative.
CONCLUSIONS:Most of the patients with Pulmonary epithelial-myoepithelial carcinoma have a good prognosis. Diagnosis mainly depends on microscopic examination and immunohistochemistry. The treatment of pulmonary epithelial-myoepithelial carcinoma is mainly surgical resection. The effect of radiotherapy and chemotherapy is not clear.
