Differential diagnosis of motor neuron disease
10.3760/cma.j.issn.1006?7876.2019.10.009
- VernacularTitle:运动神经元病的鉴别诊断
- Author:
Ling LIAN
1
;
Xiaoli YAO
Author Information
1. 中山大学附属第一医院神经科(广东省重大神经疾病诊治研究重点实验室)
- Keywords:
Motor neuron disease;
Amyotrophic lateral sclerosis;
Upper motor neuron;
Lower motor neuron;
Differential diagnosis
- From:
Chinese Journal of Neurology
2019;52(10):841-846
- CountryChina
- Language:Chinese
-
Abstract:
Motor neuron disease (MND) is a type of chronic progressive neurodegenerative disease involving upper and/or lower motor neurons, including amyotrophic lateral sclerosis, progressive bulbar palsy, primary lateral sclerosis, progressive muscular atrophy, and spinal muscular atrophy. Different types of motor neuron diseases have distinct characteristics. Therefore, the diagnosis mainly depends on clinical manifestations, physical examination and electrophysiological examination, and is made by exclusion of other diseases. Atypical cases are sometimes difficult for clinical physicians to distinguish from other diseases involving upper and/or lower motor neurons. This article is going to introduce various types of MND and their differential diagnosis according to site of lesion of motor neuron disease.
