Comparison of ultrasound radiomics with conventional imaging models :diagnosis of central cervical lymph node metastasis in papillary thyroid carcinoma
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1004‐4477.2019.10.011
   		
        
        	
        		- VernacularTitle:超声影像组学与传统影像模式对甲状腺乳头状癌颈部中央区淋巴结转移的诊断价值比较
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yunxia HUANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jin ZHOU
			        		
			        		;
		        		
		        		
		        		
			        		Tongtong LIU
			        		
			        		;
		        		
		        		
		        		
			        		Yi GUO
			        		
			        		;
		        		
		        		
		        		
			        		Yuyang TONG
			        		
			        		;
		        		
		        		
		        		
			        		Jinhua YU
			        		
			        		;
		        		
		        		
		        		
			        		Yuanyuan WANG
			        		
			        		;
		        		
		        		
		        		
			        		Min CHEN
			        		
			        		;
		        		
		        		
		        		
			        		Shichong ZHOU
			        		
			        		;
		        		
		        		
		        		
			        		Cai CHANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 复旦大学附属肿瘤医院超声科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Ultrasonography;
			        		
			        		
			        		
				        		Radiomics;
			        		
			        		
			        		
				        		Papillary thyroid carcinoma;
			        		
			        		
			        		
				        		Lymph node metastasis;
			        		
			        		
			        		
				        		Central neck;
			        		
			        		
			        		
				        		Computer tomography
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Ultrasonography
	            		
	            		 2019;28(10):882-887
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To compare the difference of diagnostic ability between ultrasound radiomics ( USR) and different conventional imaging models of central neck ( Ⅵ ) lymph node metastasis in papillary thyroid carcinoma ( PTC) . Methods A training set of 609 cases was set up . USR features were extracted and screened by USR method . A weighted formula was established to calculate the USR score of each patient by ultrasound image . T he USR score of the best diagnostic ability was obtained by statistical method and set as the diagnostic criterion . A test set of 326 cases was established to compare the diagnostic ability of USR score with ultrasound ( US ) ,computed tomography ( CT ) and US combined CT . Results T he accuracy ,sensitivity ,specificity ,area under ROC curve and Youden index of USR score in test set were 0 .804 ,0 .867 ,0 .770 ,0 .766 ,0 .533 ,respectively ,which were significantly higher than the corresponding values of US ,CT and US combined CT ( all P = 0 .000 ) . Conclusions USR score obtained with USR method can effectively predict lymph node metastasis in Ⅵ region of PTC . T he diagnostic efficiency and clinical value of USR score were significantly higher than those of conventional medical imaging models .