Study on quality standard of Compound Belladonna Mixture
10.3969/j.issn.1006-0111.2017.03.015
- VernacularTitle:复方颠茄合剂质量标准研究
- Author:
Xiaoxuan TAO
1
;
Gang LI
;
Lan XU
;
Qiang ZHANG
Author Information
1. 解放军94医院药学科
- Keywords:
TLC;
HPLC;
morphine;
quality standard
- From:
Journal of Pharmaceutical Practice
2017;35(3):256-258
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the quality standard for Compound Belladonna Mixture.Methods TLC was used for the qualitative identification of morphine.HPLC was used for the content of morphine in the Compound Belladonna Mixture.Results Morphine could be identified by TLC.A good linear correlation of morphine was observed within the range of 0.525~10.5 μg/ml (r=0.999 9).The average recovery was 99.44% with RSD of 0.23% (n=9).Conclusion This method is simple,accurate and quick, which could be used for determination and quality control of Compound Belladonna Mixture with good selectivity and repeatability.
