Optimization of the water extraction process for Zhuyu Zhitong gel paste by or-thogonal experiment
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1006-0111.2017.02.012
   		
        
        	
        		- VernacularTitle:正交试验优选逐瘀止痛凝胶膏剂的水提工艺研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Dong YANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jianyun BI
			        		
			        		;
		        		
		        		
		        		
			        		Yanwei GUO
			        		
			        		;
		        		
		        		
		        		
			        		Zhenyu ZHANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 潍坊市益都中心医院
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Zhuyu Zhitong;
			        		
			        		
			        		
				        		gel paste;
			        		
			        		
			        		
				        		paeoniflorin;
			        		
			        		
			        		
				        		orthogonal experiment
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Pharmaceutical Practice
	            		
	            		 2017;35(2):146-149
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To study the water extraction process of Zhuyu Zhitong gel paste .Methods With the yields of paeoniflorin and the dry paste as target ,the water extraction process of Zhuyu Zhitong gel paste was optimized by an orthogo-nal experimental design based on the single factor experiment .Results The optimized water extraction process of Zhuyu Zhi-tong gel paste was soaking the materials for 1 h with 8 times of water ,then extracting 1 .5 h for three times with the same a-mount of water .Conclusion The optimized extraction process was consistent ,reasonable and feasible for large production .