Research progress on total synthesis and activity of nitidine
10.3969/j.issn.1006-0111.2017.02.002
- VernacularTitle:两面针碱全合成及活性研究进展
- Author:
Zeng ZHAO
1
;
Hao CHEN
;
Niao YANG
;
Qingyan SUN
;
Runhui LIU
Author Information
1. 第二军医大学药学院天然药化教研室
- Keywords:
nitidine;
total synthesis;
bioactivity;
mechanism of action
- From:
Journal of Pharmaceutical Practice
2017;35(2):102-107,149
- CountryChina
- Language:Chinese
-
Abstract:
Nitidine is a benzophenanthridine alkaloid derived from Zanthorulum nitidum (Roxb .) DC root .Research shows that nitidine displays rich biological activities ,such as anti-tumor ,anti-inflammatory ,anti-malaria and etc .This paper reviewed the progress of the total synthesis methods for nitidine and recent research on bioactivities .
