Re-evaluation on preparation technology of compound Chuanxiong dropping pills
10.3969/j.issn.1006-0111.2015.01.016
- VernacularTitle:复方川芎滴丸制备工艺再探讨
- Author:
Wei ZHANG
1
;
Yan WEI
;
Shoujiang MA
Author Information
1. 解放军107医院药剂科
- Keywords:
compound Chuanxiong dropping pill;
preparation technology;
orthogonal test
- From:
Journal of Pharmaceutical Practice
2015;(1):60-62
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the preparation technology of compound Chuanxiong dropping pills .Methods Ratio of intermediate material to matrix ,dripping temperature and condensate temperature were used as factors ,with spherical de‐gree ,pill weight variatcon ,dissolve time limit coefficient and appearance quality as indexes ,the forming technology of compound Chuanxiong dropping pill was optimized by orthogonal test .The dropping preparation technology was optimized using dropping distance ,dropping speed as factors .Results The optimal preparation conditions were as follows:ratio of intermediate material to matrix was 1:2 ,dropping temperature was 80 ℃ ,temperature of condensate was 15‐20 ℃ ,dropping distance was 5 cm , dropping speed was 40 drops/min .Conclusion The preparation technology was reasonable ,simple and easy to control for the preparation of compound Chuanxiong dropping pills .
