A Case of Portal Vein Thrombosis by Protein C and S Deficiency Completely Recanalized by Anticoagulation Therapy
10.4068/cmj.2011.47.3.185
- Author:
Bo Kyoung CHOI
1
;
Soo Hyun YANG
;
Kang Hum SUH
;
Jin Ah HWANG
;
Moon Hyung LEE
;
Won Keun SI
;
Ji Ho KIM
Author Information
1. Department of Internal Medicine, Seoul Veterans Hospital, Seoul, Korea. nysh33@naver.com
- Publication Type:Case Report
- Keywords:
Protal vein;
Thrombosis;
Protein C deficiency;
Protein S deficiency;
Anticoagulation
- MeSH:
Anticoagulants;
Heparin, Low-Molecular-Weight;
Hypertension, Portal;
Liver Transplantation;
Portal Vein;
Protein C;
Protein C Deficiency;
Protein S Deficiency;
Thrombosis;
Venous Thrombosis
- From:Chonnam Medical Journal
2011;47(3):185-188
- CountryRepublic of Korea
- Language:English
-
Abstract:
Portal vein thrombosis (PVT) is a rare form of venous thrombosis that affects the hepatic portal vein flow, which can lead to portal hypertension. Treatment of PVT includes anticoagulants, thrombolysis, insertion of shunts, bypass surgery, and liver transplantation. Single anticoagulation therapy is not regarded as a curative treatment but can be associated with a reduction in new thrombotic episodes. We experienced a case of acute total occlusion of PVT provoked by protein C and S deficiency syndrome. PVT was completely recanalized with oral anticoagulant therapy following low molecular weight heparin therapy.