Deep Vein Thrombosis in Patients with Pulmonary Embolism: Prevalance, Clinical Significance and Outcome.
10.5758/vsi.2016.32.4.166
- Author:
Jun Sung LEE
1
;
Tong MOON
;
Tae Hoon KIM
;
Se Young KIM
;
Jun Young CHOI
;
Kyung Bok LEE
;
Yu Jin KWON
;
Suk Hee SONG
;
Su Hyun KIM
;
Hae Ok KIM
;
Ho Kyeong HWANG
;
Min Ji KIM
;
Young Kyoung LEE
Author Information
1. Department of Surgery, Seoul Medical Center, Seoul, Korea. kblee0925@me.com
- Publication Type:Original Article
- Keywords:
Venous thrombosis;
Pulmonary embolism;
Prevalence;
Outcome;
Risk factors
- MeSH:
Anoxia;
Heart Rate;
Humans;
Hypotension;
Mass Screening;
Mortality;
Oxygen;
Prevalence;
Pulmonary Embolism*;
Risk Factors;
Shock;
Tachycardia;
Venous Thrombosis*
- From:Vascular Specialist International
2016;32(4):166-174
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Deep venous thrombosis (DVT) and pulmonary embolism (PE) are considered as similar disease entities representing different clinical manifestations. The objectives of this study were: 1) to determine the prevalence and outcome of DVT in patients with PE; 2) to identify additional risk factors for PE-related unfavorable outcome and 30-day all-cause mortality; and 3) to establish the clinical importance of screening for concomitant DVT. MATERIALS AND METHODS: From January 2013 to December 2015, a total of 141 patients with confirmed PE were evaluated. The prevalence and outcome of DVT in patients with PE was determined. Furthermore, the potential risk factors for PE-related unfavorable outcome and 30-day all-cause mortality were also analyzed. RESULTS: The prevalence of concomitant DVT was 45.4%. PE-related unfavorable outcome was observed in 21.9% of all concomitant DVT, with all-cause mortality of 21.9%. There was no significant relationship between the presence of concomitant DVT and the development of PE-related unfavorable outcome or all-cause mortality. Our results indicated that heart rate >100/min and peripheral oxygen saturation <90% were independent predictors for PE-related unfavorable outcome. Regarding all-cause mortality, active malignancy and hypotension or shock were significant risk factors. CONCLUSION: Our findings demonstrate that approximately half of patients with PE possess DVT. However, this study failed to establish any clinical significance of concomitant DVT for PE-related unfavorable outcome and all-cause mortality. Tachycardia and hypoxemia were identified as significant predictors for PE-related unfavorable outcome along with active malignancy and hypotension or shock as significant risk factors of all-cause mortality.
