Association between Metabolic Syndrome and Severity of Depression Scored with Patient Health Questionnaire-9 in Men Older Than 50 Years
	    		
		   		
		   			
		   		
	    	
    	 
    	10.21215/kjfp.2019.9.5.467
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Minsik LEE
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Family Medicine, Serim General Hospital, Incheon, Korea. misrandil15749@gmail.com
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Metabolic Syndrome;
			        		
			        		
			        		
				        		National Institutes of Health;
			        		
			        		
			        		
				        		Depression;
			        		
			        		
			        		
				        		Patient Health Questionnaire;
			        		
			        		
			        		
				        		The Sixth Korea National Health and Nutrition Examination Survey
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Blood Pressure;
				        		
			        		
				        		
					        		Body Mass Index;
				        		
			        		
				        		
					        		Centers for Disease Control and Prevention (U.S.);
				        		
			        		
				        		
					        		Cholesterol;
				        		
			        		
				        		
					        		Depression;
				        		
			        		
				        		
					        		Education;
				        		
			        		
				        		
					        		Fasting;
				        		
			        		
				        		
					        		Glucose;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Korea;
				        		
			        		
				        		
					        		Lipoproteins;
				        		
			        		
				        		
					        		Male;
				        		
			        		
				        		
					        		National Institutes of Health (U.S.);
				        		
			        		
				        		
					        		Nutrition Surveys;
				        		
			        		
				        		
					        		Odds Ratio;
				        		
			        		
				        		
					        		Prevalence;
				        		
			        		
				        		
					        		Triglycerides;
				        		
			        		
				        		
					        		Waist Circumference
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:
	            		
	            			Korean Journal of Family Practice
	            		
	            		 2019;9(5):467-470
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:Korean
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	BACKGROUND: This study aimed to evaluate the association between metabolic syndrome and depression severity based on the Patient Health Questionnaire 9 (PHQ-9) score in men aged >50 years.METHODS: In this study, we used data of 1,230 individuals from the Sixth Korea National Health and Nutrition Examination Survey (KNHANES VII-1) 2016 conducted by the Korea Centers for Disease Control and Prevention. We diagnosed metabolic syndrome in accordance with National Cholesterol Education Program-Adult Treatment Panel III guidelines using waist circumference, blood pressure, fasting serum triglyceride level, high-density lipoprotein cholesterol level, and fasting glucose level in men aged >50 years (mean±standard deviation: 64.6±8.8 years), and their PHQ-9 scores were classified as mild and severe (cutoff, 10).RESULTS: The mean waist circumference, fasting glucose level, triglyceride level, and high-density lipoprotein cholesterol level were 87.1±8.2 cm, 109.8±28.3 mg/dL, 155.9±123.9 mg/dL, and 46.5±12.2 mg/dL, respectively. The mean systolic and diastolic blood pressures were 124.7±15.9 mmHg and 76.2±10.7 mmHg, respectively. The mean body mass index, was 24.2±2.9 kg/m². The prevalence of metabolic syndrome was 43.7%. The mean PHQ-9 score was 2.0±3.3. The prevalence of severe depression with a score of >10 was 4.2%. Metabolic syndrome and depression were related (P<0.05). The adjusted odds ratio for metabolic syndrome was 0.5 (95% confidence interval [CI], 0.3–0.9). However, age (95% CI, 0.9–1.0), sleep duration during weekdays (95% CI, 0.9–1.0), and sleep duration during weekends (95% CI, 0.9–1.0) were not related.CONCLUSION: Metabolic syndrome was associated with depression in men aged >50 years in this study.