Incidental Detection of Parathyroid Adenoma on Somatostatin Receptor PET/CT and Incremental Role of ¹⁸F-Fluorocholine PET/CT in MEN1 Syndrome
10.1007/s13139-018-0520-2
- Author:
Saurabh ARORA
1
;
Nishikant Avinash DAMLE
;
Averilicia PASSAH
;
Madhav Prasad YADAV
;
Sanjana BALLAL
;
Vivek AGGARWAL
;
Yashdeep GUPTA
;
Praveen KUMAR
;
Madhavi TRIPATHI
;
Chandrasekhar BAL
Author Information
1. Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India. nkantdamle@gmail.com docsaurabharora@gmail.com averilicia.passah@yahoo.com, Madhav_yadav2000@yahoo.com, mail.sanjanaballal87@gmail.com, pkgaiims@gmail.com, madhavi.dave.97@gmail.com, csbal@hotmail.com
- Publication Type:Case Report
- Keywords:
¹⁸F-Fluorocholine PET/CT;
MEN1;
Gastrinoma;
Hyperparathyroidism;
¹⁷⁷Lu-DOTATATE therapy
- MeSH:
Adenoma;
Endocrine Glands;
Follow-Up Studies;
Gastrinoma;
Humans;
Hyperparathyroidism;
Islets of Langerhans;
Multiple Endocrine Neoplasia Type 1;
Neuroendocrine Tumors;
Parathyroid Neoplasms;
Parathyroidectomy;
Pituitary Gland, Anterior;
Positron-Emission Tomography and Computed Tomography;
Receptors, Somatostatin;
Somatostatin
- From:Nuclear Medicine and Molecular Imaging
2018;52(3):238-242
- CountryRepublic of Korea
- Language:English
-
Abstract:
Multiple endocrine neoplasia type 1 (MEN1) syndrome is characterized by combined occurrence of tumors of endocrine glands including the parathyroid, the pancreatic islet cells, and the anterior pituitary gland. Parathyroid involvement is the most common manifestation and usually the first clinical involvement inMEN1 syndrome, followed by gastroentero-pancreatic neuroendocrine tumors (NETs). Here we present a case where the patient initially presented with metastatic gastric NET and a single parathyroid adenoma was detected incidentally on ⁶⁸Ga-DOTANOC PET/CT done as part of post ¹⁷⁷Lu-DOTATATE therapy (PRRT) follow-up. Further ¹⁸F-fluorocholine PET/CT showed four adenomas for which the patient subsequently underwent subtotal parathyroidectomy.
