Radiation-Induced Giant Cell Granuloma Mimicking Relapsed Hodgkin Lymphoma at FDG-PET/CT
10.1007/s13139-016-0426-9
- Author:
Hugo J A ADAMS
1
;
John M H DE KLERK
;
Josien C REGELINK
;
Ben G F HEGGELMAN
;
Stefan V DUBOIS
;
Thomas C KWEE
Author Information
1. Department of Radiology and Nuclear Medicine, UniversityMedical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. h.j.a.adams@gmail.com
- Publication Type:Case Report
- Keywords:
Biopsy;
FDG-PET/CT;
Giant cell granuloma;
Hodgkin lymphoma
- MeSH:
Biopsy;
Bleomycin;
Dacarbazine;
Doxorubicin;
Female;
Follow-Up Studies;
Giant Cells;
Granuloma, Giant Cell;
Hodgkin Disease;
Humans;
Scapula;
Vinblastine;
Young Adult
- From:Nuclear Medicine and Molecular Imaging
2017;51(4):371-373
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 22-year-old woman was diagnosed with intermediate risk stage II Hodgkin lymphoma and treated with three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) followed by involved-field radiation therapy. A complete metabolic remission was achieved after two cycles of ABVD, which was maintained until three years after completion of treatment. Follow-up FDG-PET/CT four years after completion of treatment, however, showed a new FDG-avid (Deauville score of 4) lesion in the right scapula, suggesting relapsed disease. Computer tomography (CT)-guided biopsy of this lesion was performed and subsequent histological examination revealed a radiation-induced giant cell granuloma.
