Nutrient intake patterns and breast cancer risk among Jordanian women: a case-control study
- Author:
Reema Fayez TAYYEM
1
;
Reema Ibrahim MAHMOUD
;
Muna Hussien SHAREEF
;
Lina Salah MAREI
Author Information
- Publication Type:Original Article
- Keywords: Breast cancer; Diet; Nutrient pattern; Case control studies; Jordan
- MeSH: Ascorbic Acid; Breast Neoplasms; Breast; Calcium; Case-Control Studies; Diet; Female; Humans; Jordan; Marital Status; Odds Ratio; Phosphorus; Vitamin D
- From:Epidemiology and Health 2019;41(1):2019010-
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVES: Breast cancer (BC) is the most common type of cancer worldwide. Globally, BC is rapidly becoming a major common health problem among women. This study aimed to evaluate the association between nutrient intake patterns and BC risk among Jordanian women.METHODS: A total of 400 Jordanian women 20-65 years of age were recruited in this case-control study. Two hundred women recently diagnosed with BC were matched in age, income, and marital status to 200 BC-free women. A food frequency questionnaire was used to assess nutrient intake patterns.RESULTS: In this study, 3 nutrient intake patterns were identified: a high vitamin C and β-carotene nutrient intake pattern; a high calcium, phosphorus, and vitamin D nutrient intake pattern; and a high-fat nutrient intake pattern. A significant increase in BC risk was associated with the high vitamin C and β-carotene nutrient pattern (the highest for the fourth quartile; odds ratio [OR], 5.42; 95% confidence interval [CI], 2.11 to 13.91; p(trend)=0.001). In the high calcium, phosphorus, and vitamin D nutrient pattern, a significant inverse trend was detected for the risk of BC. The high-fat nutrient pattern showed a significant direct association with BC risk in the third (OR, 3.88; 95% CI, 1.58 to 9.51) and fourth (OR, 3.87; 95% CI, 1.53 to 9.77) quartiles (p(trend)=0.001).CONCLUSIONS: A significant increase in BC risk was detected for the high vitamin C and β-carotene nutrient intake pattern and the high-fat nutrient intake pattern. However, for the high calcium, phosphorus, and vitamin D nutrient intake pattern, a significant inverse trend was observed.
