Analysis of the characteristics of salvage endoscopic surgery for residual or recurrent nasopharyngeal carcinoma with different rT grading after radiotherapy
10.13201/j.issn.1001-1781.2016.06.010
- Author:
Jia Bin ZHAN
1
;
Qianhui QIU
2
Author Information
1. Graduate School of Southern Medical University, Guangzhou，510515,China;Department of Otorhinolaryngology Head and Neck Surgery,Guangdong General Hospital,Guangdong Academy of Medical Science
2. Department of Otorhinolaryngology Head and Neck Surgery,Guangdong General Hospital,Guangdong Academy of Medical Science
- Publication Type:Journal Article
- Keywords:
nasopharyngeal carcinoma;
residual or recurrent;
salvage endoscopic surgery
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2016;30(6):459-463
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the characteristics and the treatment methods of the Salvage endoscopic surgery for residual or recurrent nasopharyngeal carcinoma（rNPC）with different rT grading after irradiation failure, and to explore the effect of different endoscopic procedures on the prognosis of the diseases.Method:Ninety-six patients who underwent endoscopic salvage nasopharyngectomy for rNPC in our department between June 2009 and March 2015 were retrospectively reviewed.All the patients underwent the corresponding salvage endoscopic surgery under general anesthesia according to the different rT grading and the patients with cervical metastasis received the radical neck dissection at the same time.Result:The number of the patients whose lesions were completely removed was 44(Total removal rate 45.8%),and the number of subtotal removal was 52(subtotal removal rate 45.8%),respectively.Postoperative follow-up continued until April 2015，the median follow-up was 19 months(1-57 months),the number of overall survival patients was 62(64.6%),the number of death was 34（35.4%）. The overall 1 year survival rate(SR),2 year SR,3 year SR were 83%,68%,63%,respectively.The median survival time was 43 months.Conclusion:The patients who underwent salvage endoscopic surgery for rNPC could have a good survival rate,and the different rT grading made the different methods to resect the lesions by the endoscopy. The use of frozen pathological examination during the operation to determine the negative rate of the surgical margins is the key to ensure the operation curative effect.
