A multiomics approach to study the associations between microbial communities and functions and dental caries

Author: HUO Yuanyuan ¹ ; HAN Xuan ¹ ; LI Yuqing ¹ ; ZOU Jing ¹
Author Information

1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University
Publication Type:Review
Keywords: Dental caries; Oral microbial community; Micro-ecology; Metagenomics; Metatranscriptomics; Metaproteomics; Metabolomics
From: Journal of Prevention and Treatment for Stomatological Diseases 2018;26(3):195-199
CountryChina
Language:Chinese
Abstract: The pathogenic mechanisms by which oral microbial communities affect the occurrence and development of dental caries remain unclear. Applications that make use of high-through put sequencing technologies and metaomics approaches to research dental caries etiology can provide new ideas about disease prevention and treatment. In this article, we review advanced research presented in metaomics studies, including genomic, metagenomic, metatranscriptomic, metaproteomic and metabolomics studies of dental caries.
Full text:龋病相关微生物群落结构与功能的多组学研究进展.pdf