The concept, core theory and research methods of Chinesemedicine quality markers
10.16438/j.0513-4870.2018-0912
- VernacularTitle:中药质量标志物的概念、核心理论与研究方法
- Author:
Tie-jun ZHANG
1
;
Gang BAI
2
;
Chang-xiao LIU
1
Author Information
1. National Engineering Laboratory for Modern Preparation and Quality Control Technology of Traditional Chinese Medicine, Research Center of Quality Markers of Traditional Chinese Medicine, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China
2. College of Pharmacy, Nankai University/State Key Laboratory of Medicinal Chemical Biology, Tianjin 300353, China
- Publication Type:Research Article
- Keywords:
traditional Chinese medicine;
quality marker;
theory;
research method
- From:
Acta Pharmaceutica Sinica
2019;54(2):187-196
- CountryChina
- Language:Chinese
-
Abstract:
Q-marker is a new concept of quality control for traditional Chinese medicine. Since its introduction in 2016, it has received extensive support and participation from researchers and manufactures of the entire industry. In order to establishing the research level of quality markers, normative research model, we review the proposed core theory and research methods of Chinese medicine quality markers. The definition and scientific connotation of Chinese medicine quality markers are analyzed. The core theories and research methods of quality markers are summarized from five aspects: "effectiveness", "specificity", "transfer and traceability", "compatibility environment" and "measurability" of quality markers. This paper aims to provide useful theoretical and methodological guidance for studying Chinese medicine quality markers.
