Research progress and engineering prospect on the formulation design of 3D printing technology

VernacularTitle:3D打印制剂设计的研究进展与工程化展望
Author: Jiong ZHAO ¹ ; Meng-lao JIANG ¹ ; Yang DING ¹
Author Information

1. State Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China
Publication Type:REVIEWS
Keywords: 3D printing technology; rate-controlled drug release; time-controlled drug release; targeted drug release
From: Acta Pharmaceutica Sinica 2018;53(8):1302-1309
CountryChina
Language:Chinese
Abstract: Three-dimensional (3D) printing technology is a rapid prototyping technology for designing 3D models with special shape and complex internal structure via computer-aided/controlled drawing and preparing. This technology displays the characteristics of flexible processing, rapid shaping, low operating cost and high reliability. 3D printing technology may provide new strategies and approaches for the generation of a variety of new drug delivery systems, which makes its application in pharmaceutics attractive. This review briefly introduces the process and feature of 3D printing technology in preparation field and mainly introduces the research progress in the design and engineering of related preparations in the aspects of rate-controlled drug release, time-controlled drug release and targeted drug release. The prospects and challenges of 3D printing technology in the formulation engineering are analyzed.