Regulation of anthocyanin biosynthesis by circadian clock 
	    		
		   		
		   			
		   		
	    	
    	 
    	10.16438/j.0513-4870.2017-1167
   		
        
        	
        		- VernacularTitle:昼夜节律钟调控花青素类成分的生物合成 
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Bei-xuan HE
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Dan-dan GUO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xin-lei JIA
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Yue GAO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Mei-li GUO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. School of Pharmacy, Second Military Medical University, Shanghai 200433, China
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:REVIEWS
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		circadian rhythm clock;
			        		
			        		
			        		
				        		anthocyanins;
			        		
			        		
			        		
				        		flavonoids;
			        		
			        		
			        		
				        		biosynthesis
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Acta Pharmaceutica Sinica
	            		
	            		 2018;53(3):345-355
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	 As a secondary metabolite in plant, anthocyanins plays an important role in many aspects of plant life, and also exhibits various activities including the anti-oxidation, anti-inflammatory, antibacterial, antitumor and cardio-cerebral vascular protective in animals. They are a group of important natural drug candiadtes in the prevention of cardiovascular and cerebrovascular diseases and metabolic diseases. Therefore, exploration of the biosynthetic pathway and regulatory mechanism of anthocyanins is of great interest for improvement of anthocyanin production and development of low-cost production methods. Circadian clock, as a ubiquitous regulatory system in organisms, affects plant physiological and molecular processes, and also regulate the anthocyanin biosynthesis. To provide new ideas on anthocyanin biosynthesis, we provide a review of the recent progress in circadian rhythm clock with regard on regulation of anthocyanin biosynthesis in this paper.