Chemical constituents from Fusarium redolens, the endophytic fungus from Edgeworthia chrysantha
10.16438/j.0513-4870.2017-0016
- VernacularTitle:结香内生真菌芬芳镰刀菌化学成分的研究
- Author:
Yu-zhuo WU
1
;
Rui LI
1
;
Bo-lin QIU
1
;
Jing-fang ZHANG
1
;
Ling-yan WANG
1
;
Jun-gui DAI
1
;
Su-juan WANG
1
;
Hua-wei ZHANG
2
;
Sheng LIN
1
Author Information
1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
2. School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China
- Publication Type:ORIGINAL ARTICLES
- Keywords:
Edgeworthia chrysantha;
endophytic fungus;
Fusarium redolens;
chemical constituent;
(+)7S-deoxy-9-hydroxyphomapyrone C
- From:
Acta Pharmaceutica Sinica
2017;52(4):598-602
- CountryChina
- Language:Chinese
-
Abstract:
A new phomapyrone derivative (1), and 9 known compounds were isolated from the ethyl acetate fraction of solid fermentation of Fusarium redolens, the endophytic fungus from Edgeworthia chrysantha, by using various isolation techniques such as Sephadex LH-20, MCI GEL and Semi pre-HPLC, etc. Their structures were identified by spectroscopic analysis, including MS, UV, CD, specific rotation, IR, 1D and 2D NMR, as (+)-7S-4-deoxy-9-hydroxyphomapyrone C (1), uracil (2), uridine (3), 2'-deoxyuridine (4), adenosine (5), 2'-deoxyadenosine (6), cordysinin B (7), ergosterol (8), ergosta-5α, 8β-epidioxy-6, 22-dien-3β-ol (9), and (22E, 24S)-3α-hydroxy-24-methylcholesta-5, 8, 22-trien-7-one (10).
