The role of vitamin D and its analogues in the treatment of oral mucosal diseases and periodontal diseases
- Author:
WU Qian
1
;
WANG Jian
1
;
NIU Li
1
;
YANG Xue
1
;
TANG Xiaolin
1
Author Information
- Publication Type:Review
- Keywords: vitamin D; analogues; calcium and phosphorus metabolism; vitamin D receptor; hypercalcemia; hypercalciuria; immunity; inflammation
- From: Journal of Prevention and Treatment for Stomatological Diseases 2019;27(12):804-808
- CountryChina
- Language:Chinese
- Abstract: Vitamin D is an essential nutrient in the body. In recent years, increasing attention has been paid to its role in regulating immunity and anti-inflammatory effects. However, the application of vitamin D in vivo may produce some side effects, such as hypercalcemia and hypercalciuria. Some analogs of vitamin D obtained through molecular modification can reduce the side effects while retaining a similar regulatory action as that of vitamin D. The supplementation of vitamin D or the use of vitamin D analogs may contribute to the prevention and treatment of immune inflammatory diseases. This article reviews the role of vitamin D and its analogues in the prevention and treatment of oral mucosal diseases and periodontal diseases. The literature review results show that vitamin D and its analogues can protect the integrity of the oral mucosal barrier, prevent or delay the occurrence of oral lichen planus, and provide a reference value for the prevention and treatment of periodontitis.
- Full text:维生素D及其类似物在口腔黏膜病与牙周病治疗中的作用.pdf
