Expression of myofibroblast in gingival after orthodontic loading.
- Author:
Yao MENG
1
;
Man LIU
2
;
Qian-Nan DENG
1
Author Information
- Publication Type:Journal Article
- Keywords: gingival; myofibroblast; orthodontics; α-smooth muscle actin
- MeSH: Actins; Cell Differentiation; Collagen; Collagen Type I; Fibroblasts; Gingiva; Humans; Myofibroblasts
- From: West China Journal of Stomatology 2019;37(5):537-540
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To examine the expression of myofibroblast in gingival after orthodontic loading.
METHODS:Eight patients were selected as experimental group and treated with orthodontic force for 4 months. Ten patients were selected as the control group, were not loaded. The gingival protein expressions of collagen typeⅠ, collagen type Ⅲ, α-smooth muscle actin (α-SMA) were evaluated by immunohistochemistry method.
RESULTS:Positive expressions of collagen typeⅠ, collagen type Ⅲ were founded, while no positive staining for α-SMA in the gingival tissue except vascular epithelium before loading. In experimental group, collagen type I and collagen type Ⅲ were increased after orthodontic loading (P<0.05), the expression of α-SMA was detected and statistically significant (P<0.05).
CONCLUSIONS:The myofibroblast exists in gingival tissue after orthodontic loading, and it may be concerned with orthodontic teeth relapse.
