Liver Transplantation in Mixed Hepatocellular Carcinoma and Cholangiocarcinoma
- Author:
Jong Man KIM
1
Author Information
- Publication Type:Review
- Keywords: Liver transplantation; Liver malignancy; Outcomes
- MeSH: Biomarkers, Tumor; Carcinoma, Hepatocellular; Cholangiocarcinoma; Diagnosis; Humans; Liver Transplantation; Liver; Prognosis; Recurrence; Risk Factors; Survival Rate
- From:Journal of Liver Cancer 2019;19(2):85-90
- CountryRepublic of Korea
- Language:English
- Abstract: Mixed hepatocellular carcinoma and cholangiocarcinoma (HCC-CC) are rare tumors, and the risk factors associated with them are not well understood yet. Moreover, the diagnosis of mixed HCC-CC can be complicated due to the difficulty in distinguishing mixed HCC-CC from HCC and intrahepatic CCC on radiological images. Serum tumor markers are useful when the radiological images are inconclusive. It remains unclear whether the prognosis of mixed HCC-CC differs from that of HCC. However, several studies have reported that the tumor recurrence and patient survival rates of mixed HCC-CC were similar to those of HCC after liver transplantation (LT) and liver resection. In this paper, we report that LT in patients with mixed HCC-CC achieves outcomes which are similar to those seen in LT for HCC. Therefore, the diagnosis of mixed HCC-CC should not be considered as a contraindication for LT.
