Portal Hypertension of a Delayed Onset Following Liver Abscesses in a 12-Month-Old Infant: A Case Report and Review of the Literature
	    		
		   		
		   			
		   		
	    	
    	 
    	10.5223/pghn.2019.22.4.400
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Faisal Othman AL-QURASHI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Ahmed Abdullah ALADSANI
			        		
			        		;
		        		
		        		
		        		
			        		Fatema Khalil AL QANEA
			        		
			        		;
		        		
		        		
		        		
			        		Sarah Yousef FAISAL
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Pediatrics, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. Faisal.alqurashi@yahoo.com
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Case Report
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Portal hypertension;
			        		
			        		
			        		
				        		Esophageal and gastric varices;
			        		
			        		
			        		
				        		Liver abscess;
			        		
			        		
			        		
				        		Neonatal sepsis;
			        		
			        		
			        		
				        		Venous thrombosis
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Anti-Bacterial Agents;
				        		
			        		
				        		
					        		Catheters;
				        		
			        		
				        		
					        		Child;
				        		
			        		
				        		
					        		Enterocolitis, Necrotizing;
				        		
			        		
				        		
					        		Esophageal and Gastric Varices;
				        		
			        		
				        		
					        		Female;
				        		
			        		
				        		
					        		Hematemesis;
				        		
			        		
				        		
					        		Hemorrhage;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Hypertension, Portal;
				        		
			        		
				        		
					        		Infant;
				        		
			        		
				        		
					        		Liver Abscess;
				        		
			        		
				        		
					        		Liver;
				        		
			        		
				        		
					        		Melena;
				        		
			        		
				        		
					        		Portal Vein;
				        		
			        		
				        		
					        		Sclerotherapy;
				        		
			        		
				        		
					        		Sepsis;
				        		
			        		
				        		
					        		Umbilical Veins;
				        		
			        		
				        		
					        		Venous Thrombosis
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Pediatric Gastroenterology, Hepatology & Nutrition
	            		
	            		 2019;22(4):400-406
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	We report a 12-month-old female infant who had a history of neonatal sepsis with liver micro-abscesses that resolved with intravenous antibiotics during neonatal period. During her neonatal admission period, no umbilical vein catheter was inserted. Also, she did not undergo any abdominal surgeries or had a postnatal history of necrotizing enterocolitis. However, the child developed upper gastrointestinal bleeding in form of hematemesis and melena secondary to esophageal varices at the age of 12 months with an extra-hepatic portal vein obstruction with cavernous transformation and portal hypertension subsequently. The child underwent a successful endoscopic injection sclerotherapy. She is now 20-month-old and has portal hypertension but otherwise asymptomatic. We are proposing the possibility of a delayed-onset portal hypertension as a complication of liver abscess and neonatal sepsis.