External quality assessment of prenatal screening for maternal serum inhibin A in second trimester
10.3760/cma.j.issn.1007-9408.2019.05.009
- VernacularTitle:中孕期母血清产前筛查抑制素A检测室间质量调查结果分析
- Author:
Yuxuan DU
1
;
Jianming FENG
;
Wei WANG
;
Falin HE
;
Kun ZHONG
;
Shuai YUAN
;
Jiali LIU
;
Zhixin ZHANG
;
Zhiguo WANG
Author Information
1. 北京医院国家老年医学中心 卫生部临床检验中心 北京市临床检验工程技术研究中心 100730
- Keywords:
Inhibins;
Prenatal diagnosis;
Clinical laboratory techniques;
Quality control;
Pregnancy trimester,second
- From:
Chinese Journal of Perinatal Medicine
2019;22(5):341-344
- CountryChina
- Language:Chinese
-
Abstract:
Objective To eva1uate the external quality assessment results of prenatal screening for maternal serum inhibin A in the second trimester in 2018 and to improve the accuracy of prenatal screening.Methods National Center for Clinical Laboratories provided three batches of quality control urine sample (Lot:201811-201813) to 94 prenatal screening laboratories nationwide in March 2018.Laboratories participated in the assessment voluntarily and reported the results,methods,equipment,reagents and other related information as required.Clinet EQA and Microsoft Excel 2010 were used for statistical analysis of the laboratory test results and for descriptive evaluation of the accuracy rate.Results A total of 55 laboratories submitted their testing results giving a return rate of 58.5％ (55/94),of which 52 (94.5％) were consistent with the expected results,while none of the results submitted by the other three laboratories was accurate.At the mean time,the bias of all three batches in each laboratory fell into the same side (two laboratories showed negative bias and one positive bias).Conclusions The results of the external quality assessment of prenatal screening for maternal serum inhibin A are generally satisfactory except for a few laboratories.It is necessary to incorporate prenatal screening for maternal serum inhibin A in the second trimester into the formal external quality assessment plan and regularly monitor the level of its detection quality.
