Clinical retrospective analysis in delayed graft function morbidity of kidney transplantation recipients and gender factors in both donors and recipients
10.3760/cma.j.issn.0254-1785.2019.07.008
- VernacularTitle:供、受者性别因素与受者移植肾功能延迟恢复发生率的临床回顾性分析
- Author:
Dawei ZHOU
1
;
Juntao LIANG
;
Yanfeng WANG
;
Guizhu PENG
;
Shaojun YE
;
Zhiping XIA
;
Xiaoyan HU
;
Qifa YE
Author Information
1. 武汉大学中南医院 武汉大学肝胆疾病研究院 武汉大学移植医学中心 移植医学技术湖北省重点实验室 430071
- Keywords:
Kidney transplantation;
Gender;
Estrogen
- From:
Chinese Journal of Organ Transplantation
2019;40(7):414-418
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of donor/recipients' gender on delayed graft function (DGF) .Methods A retrospective analysis was performed for clinical data of donors (n=174) and recipients (n=265) during renal transplantation between May 1 ,2012 and December 31 ,2017 . Types of China donation after citizen's death ,age ,last creatinine level ,height ,weight ,body mass index (BMI) and protopathy of donors were collected .And pre-dialysis method ,dialysis time ,HLA mismatch ,post-creatine at Day 7 ,whether dialysis after transplantation ,height ,weight and BMI of recipients were analyzed .The data were checked by t and chi square tests and P<0 .05 was deemed as statistically significant .Results Donor gender had no correlation with DGF occurrence rate ( P=0 .689) while DGF occurrence rate among female recipients was evidently lower than that among males (P=0 .036);Female recipients selected peritoneal dialysis therapy more than male recipients (P=0 .023);Cerebral hemorrhage female donors were more than male donors (P= 0 .034);BMI (P<0 .001) and postoperative creatinine (P= 0 .001) among female recipients were evidently lower than that among males .Conclusions DGF occurrence rate is significantly lower among female receptors than that among males after kidney transplantation .
