Detection of skin thickness and echo density in healthy adults by using high-frequency ultrasound
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.0412-4030.2019.06.008
   		
        
        	
        		- VernacularTitle:高频超声检测健康成人皮肤厚度及回声密度
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Ruixing YU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Ke XUE
			        		
			        		;
		        		
		        		
		        		
			        		Xue SHEN
			        		
			        		;
		        		
		        		
		        		
			        		Yong CUI
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 中日友好医院皮肤病与性病科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Ultrasonography;
			        		
			        		
			        		
				        		Epidermis;
			        		
			        		
			        		
				        		Dermis;
			        		
			        		
			        		
				        		Skin thickness;
			        		
			        		
			        		
				        		Skin echo density
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Dermatology
	            		
	            		 2019;52(6):414-419
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective To measure the thickness and echo density of the skin at multiple sites of healthy adults by using high-frequency ultrasound.Methods A total of 50 healthy volunteers were enrolled from Department of Dermatology and Venereology,China-Japan Friendship Hospital between June and December in 2018,including 33 females and 17 males aged 22-69 years.The thickness and echo density of the epidermis,dermis and epidermis-dermis layer were detected by using high-frequency ultrasound at 12 sites,including the forehead,cheek,chest,abdomen,and the inner and outer sides of the upper arm,forearm,thigh and leg.The means of two groups were compared by using t test,and means of several groups were compared by using one-way analysis of variation.Results High-frequency skin ultrasound images differed among different anatomical sites.There were significant differences in the thickness and echo density of the epidermis,dermis and epidermis-dermis layer among the 12 sites (P < 0.05).The epidermis was thickest at the inner side of the thigh (160.68 μm ± 25.71 μm),the dermis was thickest at the cheek(1 828.78 μm ± 399.10 μm),and the epidermis-dermis layer was thickest at the cheek (1 943.48 μm ± 402.4 μm).The echo density of the epidermis,dermis and epidermis-dermis layer was highest at the inner side of the leg (152.27 ± 21.56),forearm (52.71 ± 15.57) and forearm (62.56 ± 15.76) respectively.The thickness of the epidermis,dermis and epidermis-dermis layer at the forehead,cheek and the inner side of the forearm was significantly higher in male volunteers than in female volunteers (P ≤ 0.05 or < 0.01),while the echo density of the dermis and epidermis-dermis layer at the forehead,cheek and the outer side of the leg was significantly lower in male volunteers than in female volunteers (P < 0.05 or 0.01).Conclusion Differences exist in skin thickness and echo density among different anato mical sites and between male and female healthy adults.