Progress on biomarkers of sepsis
10.3760/cma.j.issn.1674-2397.2019.02.012
- VernacularTitle:脓毒症生物学标志物的研究进展
- Author:
Suzhen JIANG
1
;
Guiqiang WANG
Author Information
1. 北京大学国际医院感染疾病科102206
- Keywords:
Sepsis;
Biomarker;
Innate immunity;
Cytokine
- From:
Chinese Journal of Clinical Infectious Diseases
2019;12(2):142-147
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is now defined as life-threatening organ dysfunction due to a dysregulated host response to infection.The identification of pathogen is usually time-consuming.Besides, it has a low positivity rate in diagnosis of sepsis.Thus, it’s crucial to find suitable biomarkers for early diagnosis , prognosis and evaluation of treatment effect of sepsis.This article reviews the diagnostic value of pro-inflammatory cytokines, anti-inflammatory cytokines,surface receptors of immune cells in nature immunity in sepsis.