Advances in the pathogenesis and prediction models after intravenous thrombolysis secondary hemorrhagic transformation
10.3760/cma.j.issn.1008-1372.2019.05.047
- VernacularTitle:静脉溶栓后继发出血转化的发病机制及预测模型研究进展
- Author:
Cailing WANG
1
;
Juan FENG
Author Information
1. 中国医科大学附属盛京医院神经内科
- Keywords:
Brain infarction;
Administration,intravenous;
Thrombolytic therapy;
Tissue plasminogen activator;
Cerebral hemorrhage;
Models,statistical;
Review
- From:
Journal of Chinese Physician
2019;21(5):795-797
- CountryChina
- Language:Chinese
-
Abstract:
Intravenous thrombolysis is one of the most effective methods for the treatment of acute cerebral infarction.However,secondary hemorrhagic transformation after thrombolysis is a serious complication.Many studies have shown that hypofibrinemia and severe damage to the blood-brain barrier are important causes of this result.Bleeding after thrombolysis is not caused by a single factor.Foreign countries have more predictive research models for hemorrhagic transformation.Various research results have their own advantages and disadvantage.Domestic research is still scarce.This article reviews the pathogenesis,classification and prediction models of hemorrhagic transformation after intravenous thrombolysis.
