Study on attention cognitive function and event-related potential in the children with the first-episode tic disorder

VernacularTitle:首发单纯抽动障碍患儿注意认知的事件相关电位研究
Author: Yili ZHANG ¹ ; Yanling REN ; Ling MA ; Jing CAI ; Suhong WANG
Author Information

1. 苏州大学附属第三医院脑科学研究中心
Keywords: Tic disorder; Oddball task; P300; P3a; P3b; Attention
From: Chinese Journal of Behavioral Medicine and Brain Science 2019;28(5):427-430
CountryChina
Language:Chinese
Abstract: Objective To explore the changes of attention cognitive function by studying Oddball task behavior and event-related potentials(ERPs) in children with first-episode tic disorder(TD). Methods Oddball task was tested in 30 children with TD and 30 normal children,and their behavioral data and P3a/P3b components of ERPs were analyzed. Results Children with TD had a lower hitting number (49(48, 50)) than control group (50(49,50),P<0. 05). The main effect of group ( F=6. 047,P=0. 015) and the interaction effect between group and condition (F=4. 619,P=0. 034) on the amplitude of P3a were signifi-cant(P<0. 05). The amplitude of P3a component ((5. 91±4. 51)μV ) in TD group were smaller than that in the control group((9. 57±5. 80)μV)(P<0. 05). However,there was no significant interaction effect be-tween group and condition on P3a latency,P3b amplitude and latency (P>0. 05). Conclusion Attentional orienting is impaired in children with TD.