Experience of continuous fluid therapy in successfully rescuing a patient with acute severe paraquat poisoning
10.3760/cma.j.issn.2095-4352.2019.08.027
- VernacularTitle:持续补液成功抢救1例急性重度百草枯中毒患者经验总结
- Author:
Enmin FENG
1
;
Youlin CHENG
;
Zhihua TAN
;
Hailing WANG
Author Information
1. 潍坊医学院附属寿光市人民医院重症医学科 262700
- Keywords:
Paraquat;
Poisoning;
Fluid therapy
- From:
Chinese Critical Care Medicine
2019;31(8):1043-1044
- CountryChina
- Language:Chinese
-
Abstract:
Paraquat (PQ) poisoning has become one of the common pesticide poisoning in China. PQ is extremely toxic to human beings. The fatality rate of oral PQ poisoning is more than 90%. So far, there is no specific antidote. Seek effective treatment measures for PQ poisoning has become the focus of clinical medical research. In November 2017, a patient with acute severe PQ poisoning was treated in the intensive care unit (ICU) of Shouguang People's Hospital Affiliated to Weifang Medical College. The patient refused blood purification therapy and was rescued successfully only by continuous fluid therapy, diuresis, catharsis and routine treatment. By reviewing the treatment process of this case, new treatment ideas for the clinical treatment of PQ poisoning in primary hospitals were provided. Patients with acute PQ poisoning should be rescued by immediate administration of emetic, gastric lavage, catharsis and oral montmorillonite powder. For those without dysfunction of heart, lung and and kidney, a large amount of fluid treatment and diuresis should be given immediately to promote the excretion of poison. The key to improve the success rate of rescue of acute PQ poisoning is to eliminate PQ from the body as soon as possible.
