Roles of HOXC gene in tumors
10.3760/cma.j.issn.1673-422X.2019.03.011
- VernacularTitle:HOXC基因在肿瘤中的作用
- Author:
Jingzhang LI
1
;
Bingqiang NI
Author Information
1. 广西壮族自治区柳州市人民医院肿瘤内科 545006
- Keywords:
Neoplasms;
Genes,homeobox;
HOXC
- From:
Journal of International Oncology
2019;46(3):181-185
- CountryChina
- Language:Chinese
-
Abstract:
The protein encoded by the HOXC gene regulates multiple processes during embryonic development,including cell growth,differentiation,apoptosis,migration and angiogenesis.The HOXC gene is also involved in the occurrence and development of various human solid tumors,such as colorectal cancer,gastric cancer,liver cancer,breast cancer,endometrial cancer,etc.In addition,the HOXC gene is closely related to the clinical stage and distant metastasis of the tumor.Thus,the HOXC gene can be used as a biological predictor of tumor metastasis and prognosis.
