Diagnosis and management of granular cell tumor of the larynx.
- Author:
Dan LV
1
;
Shixi LIU
;
Rong YU
;
Yuanzhi ZHU
;
Hui YANG
Author Information
1. Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
- Publication Type:Case Reports
- MeSH:
Adult;
Diagnosis, Differential;
Female;
Granular Cell Tumor;
diagnosis;
Humans;
Laryngeal Neoplasms;
diagnosis;
Male;
Middle Aged;
Retrospective Studies
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2013;27(3):116-118
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the histogenesis, morphological features and biologic behaviors of granular cell tumor(GCT) of the larynx.
METHOD:A retrospective study was performed in three cases of GCT in our hospital, the clinical data were studied with histopathologic analysis, histochemical and immunohistochemical staining, and combining with the analysis of domestic and foreign literatures.
RESULT:Histopathologic features of laryngeal GCT were identical to that in soft tissues, but pseudoepitheliomatous hyperplasia was present in 50%-60% cases of the tumor. This disease may originate from the neurogenic Schwann cell, S-100 could be positive in immunohistochemistry.
CONCLUSION:Laryngeal GCT is a rare benign tumor and can be cured by local excision.
