Analysis of the nutritional status and nosocomial infection during chemoradiotherapy in advanced nasopharyngeal carcinoma patients.
- Author:
Jie LIU
;
Jianxuan LIAO
;
Qiao YANG
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Carcinoma;
Combined Modality Therapy;
Cross Infection;
epidemiology;
Female;
Humans;
Male;
Middle Aged;
Nasopharyngeal Carcinoma;
Nasopharyngeal Neoplasms;
drug therapy;
microbiology;
radiotherapy;
Nutritional Status;
Risk Factors
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2014;28(3):188-191
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the nutritional status and nosocomial infection of nasopharyngeal carcinoma patients before and after the chemoradiotherapy treatment.
METHOD:An analysis was made for the nutritional and nosocomial infection status of 82 cases before and after chemoradiotherapy treatment.
RESULT:Statistically significant differences were revealed between indexes related with nutritional status such as body mass, hemoglobin, serum albumin before and after the treatment. Sixty-three patients occurred nosocomial infection. The infection rate was 76.83%. The main risk factor was oropharynx mucosal lesion and the rate is 92.68%. Isolates of 39 bacteria were found, of which Gram-negative organisms were 58.97%, Fungi were 30.77%, Gram-positive ones were 7.69%, Herpes zoster were 2.56%.
CONCLUSION:Chemoradiotherapy has negative influence on nutritional status of patients. Medical personnel should pay attention to patients' nutritional status and do a good job of nutritional status monitoring, nutrition support, dieting guidance, reducing side effects, in order to improve the patient's tolerability and quality of life. The nosocomial infection rate of Gram-negative bacteria of oropharyngeal mucosal is the highest in patients with advanced nasopharyngeal cancer during chemoradiotherapy. It is very important for us to prevent and control nosocomial infection.
