Surgical treatment of differentiated thyroid carcinoma with laryngeal or tracheal invasion.
- Author:
Xinbo XU
;
Wenming LI
;
Tong JIN
;
Ye QIAN
;
Dongmin WEI
;
Ruijie SUN
;
Dayu LIU
;
Dapeng LEI
;
Xinliang PAN
- Publication Type:Journal Article
- MeSH:
Adenocarcinoma;
Humans;
Laryngectomy;
Larynx;
pathology;
Larynx, Artificial;
Neoplasm Invasiveness;
Prognosis;
Quality of Life;
Retrospective Studies;
Survival Rate;
Thyroid Neoplasms;
pathology;
surgery;
Trachea;
pathology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2014;28(24):1934-1937
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the clinical characters, surgical treatments and prognosis of differentiated thyroid carcinoma (DTC) with laryngeal or tracheal invasion.
METHOD:Forty-six cases including 33 papillary and 13 follicular were retrospectively reviewed. Thirty-four cases with tracheal invasion received conservative resection (17), window resection (11) and sleeve resection (6). One case with subglottic invasion was performed subglottic partial laryngectomy. Eleven cases with trachea-laryngeal invasion received total laryngectomy(4), 3 shave technique and 4 preservative laryngectomy.
RESULT:Complications included infections and hypocalcaemia, 15 patients got permanent fistula. 5-year survival rate in cases of tracheal shave resection was 88.2%, while 63.6% in those of window resection and 83.3% in those of sleeve resection. Survival rate within 5 years of patients received preservative laryngectomy was 62. 5%. Conclusion: With meticulous preoperative examination and positive surgical treatment, both survival rate and quality of life could be improved in patients of DTC with laryngeal or tracheal invasion.
