Round window catheter placement with dexamethasone perfusion for intractable sudden sensorineural hearing loss.
	    		
		   		
	    	
    	
    	
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Xialing SUN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jihao REN
			        		
			        		;
		        		
		        		
		        		
			        		Yongde LU
			        		
			        		;
		        		
		        		
		        		
			        		Tuanfang YIN
			        		
			        		;
		        		
		        		
		        		
			        		Weijing WU
			        		
			        		;
		        		
		        		
		        		
			        		Yueying TANG
			        		
			        		;
		        		
		        		
		        		
			        		Binya HU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Otolaryngology, the Second Hospital of Xiangya Medical College, Central South University, Changsha, 410011, China.
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Adult;
				        		
			        		
				        		
					        		Aged;
				        		
			        		
				        		
					        		Catheterization;
				        		
			        		
				        		
					        		Dexamethasone;
				        		
			        		
				        		
					        		administration & dosage;
				        		
			        		
				        		
					        		therapeutic use;
				        		
			        		
				        		
					        		Female;
				        		
			        		
				        		
					        		Hearing Loss, Sensorineural;
				        		
			        		
				        		
					        		drug therapy;
				        		
			        		
				        		
					        		Hearing Loss, Sudden;
				        		
			        		
				        		
					        		drug therapy;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Male;
				        		
			        		
				        		
					        		Middle Aged;
				        		
			        		
				        		
					        		Round Window, Ear
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:
	            		
	            			Journal of Clinical Otorhinolaryngology Head and Neck Surgery
	            		
	            		 2007;21(4):146-148
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	OBJECTIVE:To investigate the efficacy of round window catheter placement with dexamethasone perfusion for 13 patients with intractable sudden sensorineural hearing loss (SSNHL).
				        	
				        
				        	METHOD:Dexamethasone (2.5 mg) was perfused transtympanically through round window catheter by Micro-infusion pump. The perfusion was taken twice a day and continued for an hour each time, for a total of 7 days.
				        	
				        
				        	RESULT:Thirteen patients have been followed up for 1 month. Five of them (38.5%) were demonstrated a 17-54 dB improvement in pure-tone threshold average (PTA). The other 8 patients (61.5%) had no effect.
				        	
				        
				        	CONCLUSION:Round window catheter placement with dexamethasone perfusion is a cost-effective and useful treatment for SSNHL patients who had no effect through conventional therapy, although hearing thresholds of these patients had hardly improved to normal levels.