The significance of the expression of Col IV and LN in nasal and paranasal sinus malignant tumor.
- Author:
Tinseak MOK
1
;
Yanchun SHAN
;
Haiying JIA
;
Tao ZHANG
;
Jiqun WANG
Author Information
1. Department of Otorhinolaryngology, Central Hospital Conde De S. Januario, Macau, China. moktinseak@gmail.com
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Child;
Collagen Type IV;
metabolism;
Female;
Humans;
Laminin;
metabolism;
Male;
Middle Aged;
Nasal Cavity;
pathology;
Nose Neoplasms;
metabolism;
pathology;
Paranasal Sinus Neoplasms;
metabolism;
pathology;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2011;25(17):771-774
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the pathological relationship between the expression of Col IV and LN in nasal and paranasal sinus malignant tumor (NPMT).
METHOD:The immunohistochemical technique was used to detected the expression of Col IV and LN in NPMT, para-cancer tissues and non-cancer tissues.
RESULT:There was a significance on the expression of the Col IV and LN in NPMT, para-cancer tissues and non-cancer tissues (P<0.01), and no significance in endepidermis and soft connective tissue of the NPMT (P>0.05).
CONCLUSION:The Col IV and LN perhaps participate in tumorigenesis of NPMT, and may play the homoioplastic role in different pathological types of the NPMT.
