Clinical findings of a group of children with auditory neuropathy spectrum disorder.
- Author:
Lingyan MO
1
;
Fei YAN
;
Hui LIU
;
Jing CHEN
;
Xueqin CHEN
;
Lihui HUANG
Author Information
1. Department of Otolaryngology, Beijing Tongren Hospital of Capital Medical University, Beijing Institute of Otolaryngology, Beijing, 100005, China. lingyanmo@gmail.com
- Publication Type:Journal Article
- MeSH:
Audiometry, Pure-Tone;
Auditory Threshold;
Child;
Child, Preschool;
Cochlear Implantation;
Female;
Hearing Loss, Central;
pathology;
physiopathology;
therapy;
Humans;
Infant;
Male;
Retrospective Studies
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2011;25(22):1012-1018
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:In order to extend the knowledge of auditory neuropathy spectrum disorder (ANSD), the clinical data of a group of infants and young children with this disorder was reported.
METHOD:This retrospective study involved 84 cases (151 ears). The subjects aged from 2 months to 6 years old. Descriptive analysis was carried out on case history, audiological and imaging results and the outcome of cochlear implantation.
RESULT:There were a variety of case history, including 11 of hyperbilirubinemia, 2 of family history of deafness, 3 of hypoxia, 1 of prematurity, 1 of nuclei basales pathology, 2 of congenital atelencephalia,and 13 of cochlear nerve deficiency (CND). The audiological results varied too. Click ABR ranged from no response at the maximum output level to Wave V thresholds as low as 70 dB nHL. Behavioral thresholds were mild in 1, moderate in 2 and profound in 20. The inner ear MRI were normal in 16 cases, CND in 12 and CND accompanied by periventricular leukomalacia in 1. 5 cases were implanted in the affected ear. The results in 3 were comparable with that of cochlear loss, 1 were less effective than that of cochlear loss, 1 became none user of the device.
CONCLUSION:ANSD is a heterogeneous group with a wide variety on case history, audiological and imaging results and the outcome of cochlear implant. Therefore, comprehensive clinical examinations are necessary so that individualized intervention program can be made.
