The long-term clinical efficacy of endoscopic surgery of primary sinonasal malignant neoplasms.
- Author:
Yudong YE
;
Qianhui QIU
;
Shuixing ZHANG
;
Yan HUANG
;
Jiandong ZHAN
;
Mimi XU
- Publication Type:Journal Article
- MeSH:
Endoscopy;
Esthesioneuroblastoma, Olfactory;
surgery;
Humans;
Nasal Cavity;
pathology;
surgery;
Nose Neoplasms;
surgery;
Proportional Hazards Models;
Retrospective Studies;
Survival Rate;
Treatment Outcome
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(12):1105-1110
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To assess the long-term clinical efficacy of endoscopic surgery of primary sinonasal malignant neoplasms and find out the potential postoperative prognostic factors.
METHOD:Forty-three clinical cases of primary sinonasal malignant neoplasms treated under endoscopy were analyzed retrospectively.
RESULT:Fifteen patients died. The 1-year, 2-year, 3-year and 5-year survival rates were 83. 7% (36/43), 74. 4% (32/43), 69. 8% (30/43) and 65. 1% (28/43), respectively. Kaplan-Meier single-variable analysis showed that gender, T grade, TNM stage and pathological types of olfactory neuroblastoma were statistically significant prognostic factors (P< 0. 05). COX Pro-Portional hazard models showed that TNM stage was an independent prognostic factors.
CONCLUSION:Endoscopic surgery for primary sinonasal malignant neoplasms is a safe and effective minimally invasive surgical treatment, and it is an important supplement to the traditional surgery. Gender, T grade, TNM stage and pathological types of olfactory neuroblastoma might be significant prognostic factors.
