Efficacy evaluation of specific immunotherapy with standardized house dust mite allergen preparation for allergic rhinitis.
- Author:
Jie ZHOU
1
,
2
;
Yuanping HE
;
Xudong ZENG
;
Zewen LI
;
Fangming PAN
;
Yingchao CHEN
;
Zhaolong LI
Author Information
1. Department of Otolaryngology, the Central of Xiaogan Hospital, Huazhong University of Science and Technology, Wuhan, 432000, China. zhoujie1115@
2. com
- Publication Type:Journal Article
- MeSH:
Allergens;
therapeutic use;
Animals;
Antigens, Dermatophagoides;
therapeutic use;
Female;
Humans;
Immunotherapy;
methods;
Male;
Pyroglyphidae;
immunology;
Rhinitis, Allergic;
therapy;
Treatment Outcome
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2012;26(11):487-489
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the efficacy of specific immunotherapy (SIT) with standardized house dust mite allergen preparation for allergic rhinitis (AR).
METHOD:Fifty-five patients with allergic rhinitis caused by house dust mites were selected in this self-control study. Clinical efficacy was evaluated by symptom and sign score after two years of specific immunotherapy and compared with pre-treatment scores.
RESULT:After completing the study, a clinically significant reduction in symptom and sign score in these patients was noted, compared with that of pretreatment. And the difference was statistically significant (P < 0.01).
CONCLUSION:Standardized house dust mite allergen preparation is an effective treatment in patients suffering from allergic rhinitis due to house dust mites.
