Transcranial magnetic stimulation relieves pain and improves cortical excitability after stroke
10.3760/cma.j.issn.0254-1424.2019.04.003
- VernacularTitle:重复经颅磁刺激对脑卒中后中枢性疼痛及皮质兴奋性的影响
- Author:
Wei SUN
1
;
Chenguang ZHAO
;
Hua YUAN
;
Xiang MU
Author Information
1. 中国人民解放军空军军医大学第一附属医院康复医学科
- Keywords:
Repetitive transcranial magnetic stimulation;
Stroke;
Pain;
Cortical excitability
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2019;41(4):252-256
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of repeatedly applying transcranial magnetic stimulation (rTMS) in treating post-stroke pain (CPSP).Methods Forty stroke survivors experiencing CPSP were randomly divided into a treatment group and a control group,each of 20.All of the patients received conventional rehabilitation.In the treatment group,20 patients received 10 Hz rTMS at 80％ of their resting motor threshold applied over the primary motor cortex on their affected side,while those in the control group received sham stimulation.Both groups were treated once a day,6 times a week for 4 weeks.Before and after the treatment,both groups were assessed using a pain score self-assessed on a visual analogue scale (VAS).Their resting motor thresholds (RMTs),cortical silent periods (CSPs) and motor evoked potentials (MEPs) were also recorded.Results After the intervention,the average VAS score,RMT,CSP and M EP latency of the treatment group were (3.1±1.2),(51.3±4.8)％,(188.9± 63.0) ms and (27.9±5.7)ms,all significantly better than those before the intervention [(5.1± 1.3),(60.1±5.9)％,(239.7±43.5) ms and (35.5±4.4)ms] (P＜0.05).They were also significantly better than those of the control group after the intervention [(4.7±1.0),(57.6±5.1)％,(241.7±33.9)ms and (31.7±5.2)ms] (P＜0.05).Conclusion Transcranial magnetic stimulation can relieve post-stroke pain.The mechanisms might be related to positive changes in cortical excitability in the affected hemisphere.
