Role of bone status in anterolateral portion of femoral head in the progression of osteonecrosis of the femoral head
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.2095-4344.1148
   		
        
        	
        		- VernacularTitle:股骨头前外侧骨质状态在股骨头坏死塌陷进展中的作用
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Qiushi WEI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Bin FANG
			        		
			        		;
		        		
		        		
		        		
			        		Zhenqiu CHEN
			        		
			        		;
		        		
		        		
		        		
			        		Mincong HE
			        		
			        		;
		        		
		        		
		        		
			        		Xiaojun CHEN
			        		
			        		;
		        		
		        		
		        		
			        		Fan YANG
			        		
			        		;
		        		
		        		
		        		
			        		Qingwen ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Wei HE
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 广州中医药大学第一附属医院三骨科保髋病区
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		osteonecrosis of the femoral head;
			        		
			        		
			        		
				        		bone structure;
			        		
			        		
			        		
				        		weight-bearing area;
			        		
			        		
			        		
				        		collapse;
			        		
			        		
			        		
				        		frog-leg lateral radiographs;
			        		
			        		
			        		
				        		imaging;
			        		
			        		
			        		
				        		bone preservation;
			        		
			        		
			        		
				        		the National Natural Science Foundation of China
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Tissue Engineering Research
	            		
	            		 2019;23(16):2516-2522
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	BACKGROUND:Mechanical stress plays an important role in the progressive collapse in osteonecrosis of the femoral head.Therefore,the bone structure of weight-bearing area may be the risk factor for collapse.OBJECTIVE:To investigate the relationship between the bone preservation of weight-bearing area and collapse progression in necrotic femoral head.METHODS:Eighty-seven patients (102 hips) with ARCO stage Ⅱ osteonecrosis of the femoral head,diagnosed by MRI,were enrolled.All patients underwent a natural progression.Collapse and bone involvement of the weight-bearing area were viewed by anteroposterior and frog-leg lateral radiographs.According to the location of the necrotic lesion on the anterolateral portion of the femoral head,the necrosis was divided into three types:type 1,the posteromedial and central portions;type 2,part of the anterolateral portion;type 3,the entire anterolateral portion.The collapse rate and the time to collapse in different types were assessed.RESULTS AND CONCLUSION:(1) All patients were followed up for 3-58 months.(2) Of the 60 hips with collapse,46 (76.7%) hip collapse was identified on anteroposterior radiograph.On frog-leg lateral radiograph showing collapsed femoral head could be identified in 57 (95.0%) hips,which was significantly different (P < 0.01).(3) In all 102 hips,the collapse rate in type 3 osteonecrosis of the femoral head was significantly higher than that of type 2 osteonecrosis of the femoral head (P < 0.001),and the time to collapse was markedly shortened.None collapse occurred in all six hips with type Ⅰ osteonecrosis of the femoral head during follow-up.(4) In summary,preservation of anterolateral portion is associated with potential collapse progression in necrotic femoral head.