Evaluation on analgesic effect of the single-injection technique of pectoral nerves Ⅰ and Ⅱ in patients undergoing modified radical mastectomy
	    		
		   		
		   			
		   		
	    	
    	 
    	10.12089/jca.2019.02.004
   		
        
        	
        		- VernacularTitle:单点注射法胸肌神经阻滞对乳腺癌改良根治术后镇痛效果的影响
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Xinman WANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Liang ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Yang LI
			        		
			        		;
		        		
		        		
		        		
			        		Yanbing YANG
			        		
			        		;
		        		
		        		
		        		
			        		Jianxin ZHANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 解放军第九六〇医院麻醉科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Ultrasound guidance;
			        		
			        		
			        		
				        		Single-injection technique;
			        		
			        		
			        		
				        		Pectoral nerves block;
			        		
			        		
			        		
				        		Modified radical mastectomy;
			        		
			        		
			        		
				        		Postoperative analgesia
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			The Journal of Clinical Anesthesiology
	            		
	            		 2019;35(2):121-124
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To investigate the efficacy of the single-injection technique of PECS Ⅰ and Ⅱ blocks for postoperative analgesia in patients undergoing modified radical mastectomy. Methods Sixty female patients who would undergo elective unilateral modified radical mastectomy, aged 30-65 years, falling into ASA physical status Ⅰ or Ⅱ, were selected and randomly divided into PECS group (group P) or control group (group C), 30 cases in each. After induction, patients in group P underwent ultrasound-guided combined PECS Ⅰ and Ⅱ blocks in a single-injection technique before surgery, 30 ml of 0.5% ropivacaine was given to these patients. Patients in group C received general anesthesia alone. Anesthesia maintenance was performed by total intravenous anesthesia. The dosage of intraoperative propofol and remifentanil, postoperative recovery time, the requirement of sufentanil at 48 h after operation and the first time pressing the analgesic pump button, rescue analgesic requirements at 48 h after operation and the pressing frequency of analgesic pump were recorded in the two groups. Results The usage of propofol and remifentanil in group P were significantly less than those in group C (P < 0.05). The recovery time after operation was significantly shorter than that in group C (P < 0.05). The total consumption of sufentanil after 48 h was significantly less than that in group C (P < 0.05). The first pressing time of the analgesic pump in group P was significantly later than that in group C (P < 0.05).The rescue analgesic requirements in group P at 48 h were lower than those in group C (P < 0.05).The pressing frequencies of analgesic pump in group P at 24 h were less than those in group C (P < 0.05). Conclusion For patients undergoing modified radical mastectomy, ultrasound-guided combined PECS Ⅰ and Ⅱ blocks in a single-injection technique can reduce the dosage of opioid drugs in the perioperative period, and can provide better analgesic effect after operation.