Animal models of Klebsiella Pneumonia infection and their applications in anti-infection of Chinese traditional medicine
10.3969/j.issn.1673-4130.2019.03.004
- VernacularTitle:肺炎克雷伯菌动物感染模型及在中药抗感染应用中的研究进展
- Author:
Juan ZHAO
1
;
Zhiyuan LIU
;
Guijian LIU
Author Information
1. 中国中医科学院广安门医院检验科
- Keywords:
Klebsiella Pneumonia;
animal models;
infection;
Chinese traditional medicine
- From:
International Journal of Laboratory Medicine
2019;40(3):269-272,276
- CountryChina
- Language:Chinese
-
Abstract:
Klebsiella pneumoniae is one of the most common bacteria in nosocomial infections, and the second pathogen in bloodstream infections and urinary tract infections.In recent years, the emergence of Carbapenem-Resistant Klebsiella Pneumonia has become the focus in the field of anti-infection.At present, the treatment of Carbapenem-Resistant Klebsiella Pneumonia is mainly combined drug use, but which exists possible drawbacks including many side effects, higher cost, and more serious drug resistance and so on.With the increasing attention of the therapeutic effect, Chinese traditional medicine begins to come into researchers′sight as an alternative therapy or combination of traditional Chinese and Western medicine.Therefore, animal models used to evaluate the efficacy of drugs have been attracted wide attention.This article reviews animal models of Klebsiella Pneumonia infection and their applications in anti-infection of Chinese traditional medicine.
