Spurious Elevation of Glucose Concentration during Administration of High Dose of Ascorbic Acid in a Patient with Type 2 Diabetes on Hemodialysis.
10.3349/ymj.2013.54.5.1289
- Author:
Soo Kyoung KIM
1
;
Jong Ryeal HAHM
;
Ho Su KIM
;
Sungsu KIM
;
Tae Sik JUNG
;
Jung Hwa JUNG
;
Hye Ryun LEE
;
Deok Ryong KIM
Author Information
1. Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea. jrhahm@gnu.ac.kr
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Self-monitoring of blood glucose;
ascorbic acid;
hypoglycemia
- MeSH:
Adult;
Ascorbic Acid/administration & dosage/adverse effects/contraindications/*therapeutic use;
Blood Glucose;
Blood Glucose Self-Monitoring/instrumentation/standards;
Diabetes Mellitus, Type 2/blood/drug therapy;
Female;
Humans;
Hypoglycemia/*diagnosis;
Renal Dialysis
- From:Yonsei Medical Journal
2013;54(5):1289-1292
- CountryRepublic of Korea
- Language:English
-
Abstract:
We describe herein a case of life-threatening hypoglycemia due to spurious elevation of glucose concentration during the administration of ascorbic acid in a type 2 diabetic patient. A 31-year-old female was admitted for proliferative diabetic retinopathy treatment and prescribed high dose ascorbic acid. During hospitalization, she suddenly lost her consciousness and her glucose concentration was 291 mg/dL, measured using self-monitoring blood glucose (SMBG) device, while venous blood glucose concentration was 12 mg/dL. After intravenous injection of 50% glucose solution, the patient became alert. We reasoned that glucose measurement by SMBG device was interfered by ascorbic acid. Physicians should be aware of this interference; high dose ascorbic acid may cause spurious elevation of glucose concentration when measuring with SMBG devices.
