Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis
- Author:
Minjeong KIM
1
;
Jin Myung PARK
;
Sung Joon LEE
;
Chang Don KANG
;
MyungHo KANG
;
Ji Hyun KIM
;
Seungkoo LEE
;
Seong Whi CHO
Author Information
- Publication Type:Case Report
- Keywords: Neuroendocrine tumor; Pancreatitis; Endoscopic ultrasound-guided fine needle aspiration
- MeSH: Abdominal Pain; Amylases; Biopsy, Fine-Needle; Biopsy, Large-Core Needle; Carcinoma, Neuroendocrine; Cholangiopancreatography, Magnetic Resonance; Chromogranin A; Dilatation; Endoscopic Ultrasound-Guided Fine Needle Aspiration; Lipase; Lymph Nodes; Neck; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreas; Pancreatic Ducts; Pancreatitis; Synaptophysin; Thorax; Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology 2018;71(2):98-102
- CountryRepublic of Korea
- Language:Korean
- Abstract: We report a case of acute pancreatitis secondary to pancreatic neuroendocrine tumor. A 46-year old man presented with upper abdominal pain. The serum amylase and lipase were elevated. Abdominal computed tomography (CT) and magnetic resonance cholangiopancreatography revealed a 1.7 cm sized mass at the pancreas body with a dilatation of the upstream pancreatic duct and mild infiltrations of peripancreatic fat. An endoscopic ultrasound-guided fine needle biopsy was performed for the pancreatic mass, but only necrotic tissue was observed on the pathologic examination. A chest and neck CT scan revealed anterior mediastinal, paratracheal, and cervical lymph node enlargement, which were indicative of metastasis. An ultrasound-guided core needle biopsy was performed for the enlarged neck lymph node, and pathologic examination revealed a metastatic poorly differentiated carcinoma. Immunohistochemical analysis showed positive staining for synaptophysin, chromogranin A, and CD 56, indicative of a neuroendocrine carcinoma.
