Clinical Application of Bone Turnover Markers in Osteoporosis in Korea
10.11005/jbm.2019.26.1.19
- Author:
So Young PARK
1
;
Seong Hee AHN
;
Jun Il YOO
;
Youn Jee CHUNG
;
Yun Kyung JEON
;
Byung Ho YOON
;
Ha Young KIM
;
Seung Hun LEE
;
Jehoon LEE
;
Seongbin HONG
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Kyung Hee University Hospital, Seoul, Korea.
- Publication Type:Review
- Keywords:
Biomarkers;
Bone remodeling;
Bone turnover markers;
Chronic kidney disease;
Osteoporosis
- MeSH:
Biomarkers;
Bone Remodeling;
Humans;
Korea;
Osteoporosis;
Renal Insufficiency, Chronic
- From:Journal of Bone Metabolism
2019;26(1):19-24
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bone turnover markers (BTMs) have important role in the management of osteoporosis. Recently the clinical application of BTMs has achieved significant progress and measurement of BTMs give us better understanding of pathogenesis of osteoporosis. However, the use of BTMs is still insufficient in Korea. We summarized the available methods and standard interval of the BTMs in Korea. Also we reviewed published literatures on pre-analytical variability in the measurement of BTMs and provided recommendations for standardized sample handling and patient preparation for reducing those pre-analytical variabilities. The clinical application of BTMs in patients with chronic kidney disease who have a higher fracture risk than the general population is summarized.
