A Case of Amyloidosis Presenting as Lymphadenopathy at the Porta Hepatis
10.7704/kjhugr.2018.18.3.209
- Author:
Ja In LEE
1
;
Joon Sung KIM
;
Byung Wook KIM
Author Information
1. Division of Gastroenterology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea. kijoons@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Amyloidosis;
Lymphadenopathy;
Multiple myeloma
- MeSH:
Amyloidosis;
Biopsy;
Bortezomib;
Dexamethasone;
Diagnosis;
Dyspepsia;
Electrophoresis;
Endoscopy, Digestive System;
Female;
Follow-Up Studies;
Humans;
Lymph Nodes;
Lymphatic Diseases;
Middle Aged;
Multiple Myeloma;
Multiple Organ Failure;
Plaque, Amyloid;
Pneumonia;
Thalidomide;
Weight Loss
- From:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
2018;18(3):209-212
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a rare case of systemic amyloidosis with gastrointestinal and lymph node involvement. A 64-year-old woman was admitted to our hospital with dyspepsia and weight loss. Initial esophagogastroduodenoscopy (EGD) revealed nonspecific findings, and abdominal computed tomography showed necrotizing lymphadenopathy at the porta hepatis. Laparoscopic lymph node biopsy was performed under suspicion of tuberculous lymphadenopathy, but a definite diagnosis was not established. Follow-up EGD performed 6 months later revealed multiple telangiectasia-like lesions at the gastric body, and endoscopic biopsy revealed amyloid deposition. Through additional blood and urine protein electrophoresis, the patient was finally diagnosed with systemic amyloidosis associated with multiple myeloma. She was treated with dexamethasone, thalidomide, and bortezomib; however, she died 3 months after diagnosis because of pneumonia and multiple organ failure.
