Computational Identification of microRNAs and Their Targets
10.3969/j.issn.1671-8135.2008.10.023
- VernacularTitle:计算识别microRNA及其靶基因
- Author:
Zhi-Yun GUO
1
;
Can-Quan MAO
;
Li-Li XIONG
Author Information
1. 西南交通大学
- Keywords:
MiRNA Bioinformatics MiRNA target
- From:
China Biotechnology
2008;28(10):118-123
- CountryChina
- Language:Chinese
-
Abstract:
The discovery of microRNAs (miRNAs) has introduced a new paradigm into gene regulatory systems. Since inception, computational methods have been an invaluable tool complementing experimental approaches, and many discoveries have been obtained through combination of experimental and computational approaches. The knowledge that has been accumulated about the principles of miRNAs and target recognition were reviewed. The currently available computational methodologies and software for prediction of miRNA and their target genes also have been discussed.
